Personal profile
Research Interests
- Working in collaboration with WHO AFRO and Ministries of Health (MoH) in Africa to generate data on the circulating rotavirus strains in the region and to support awareness and regional advocacy for the introduction of rotavirus vaccines.
- Working with team on “Rotavirus genomics and metagenomics of African stool samples” to explore in-depth genomic diversity of rotavirus strains circulating in African human and animal populations and to investigate novel diarrhoeal pathogens in African children through metagenomics
- Conduct epidemiological and surveillance studies for diarrhoeal pathogens in 5 African countries
- Conduct genetic diversity and evolutionary relationship of enteric viruses (norovirus, astrovirus, adenovirus types 40 and 41, hepatitis A and Hepatitis E)
- Conduct microbiome and metagenomics of the gut
Personal profile
I have strong background knowledge of strategy development and execution within the research directorate. My sixteen years of experience in the Department of Virology has provided me with a broad knowledge of excellence in research, teaching and administrative duties. I have earned local and international recognition in the field of viral gastroenteritis, where I have made valuable contribution in the introduction of rotavirus vaccine in South Africa and the success of the WHO rotavirus regional reference laboratory- South Africa. My duties included generating data on the circulating rotavirus strains in the in the African continent and working closely with the National Department of Health, Ministries of Health of 16 African countries and the WHO African Region (AFRO). In addition, my responsibilities have provided me an opportunity to collaboration with the National Institute of Communicable Diseases, the World Health Organization (WHO), Centers for Disease Control and Prevention in Atlanta, the University of Cincinnati, and the J Craig Venter Institute in the USA.
Education/Academic qualification
PhD, Virology, Sefako Makgatho Health Sciences University
Award Date: 7 May 2010
Keywords
- RB Pathology
- Virology
- Microbiology
- Diarrhoea
- Vaccines
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 17 Partnerships for the Goals
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Collaborations and top research areas from the last five years
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Abundance of single filamentous bacteria, and expression of differentiated Th17 cells, their signature cytokine IL-17 A, and retinoic acid receptor are predictive of poor rotavirus vaccine take
Bubuluma, R., Seheri, M. & Magwira, C. A., Dec 2025, In: Virology Journal. 22, 1, 180.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Significant abundance of bacterial flagellin and expression of its surface localized receptor toll-like receptor 5 and cytokine interleukin-22 in South African infants with poor oral rotavirus vaccine take
Haindongo, N. J., Seheri, M. & Magwira, C. A., Dec 2025, In: Gut Pathogens. 17, 1, 3.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Significant Association Between Increased Abundance of Selected Bacterial Lipopolysaccharides and Norovirus Diarrhea Among South African Infants
Kgosana, L. P., Seheri, M. L. & Magwira, C. A., Feb 2025, In: Viruses. 17, 2, 278.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Abundance of Selected Lipopolysaccharide-Rich Bacteria and Levels of Toll-like Receptor 4 and Interleukin 8 Expression Are Significantly Associated with Live Attenuated Rotavirus Vaccine Shedding among South African Infants
Kgosana, L. P., Seheri, M. L. & Magwira, C. A., Mar 2024, In: Vaccines. 12, 3, 273.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Lewis a−b− histo-blood group antigen phenotype is predictive of severe COVID-19 in the black South African population group
Magwira, C. A., Nndwamato, N. P., Selabe, G. & Seheri, M. L., 1 Jan 2024, In: Glycobiology. 34, 1, cwad090.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)