A Dynamical Study of Modeling the Transmission of Typhoid Fever through Delayed Strategies

Muhammad Tashfeen, Fazal Dayan, Muhammad Aziz Ur Rehman, Thabet Abdeljawad*, Aiman Mukheimer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

This study analyzes the transmission of typhoid fever caused by Salmonella typhi using a mathematical model that highlights the significance of delay in its effectiveness. Time delays can affect the nature of patterns and slow down the emergence of patterns in infected population density. The analyzed model is expanded with the equilibrium analysis, reproduction number, and stability analysis. This study aims to establish and explore the non-standard finite difference (NSFD) scheme for the typhoid fever virus transmission model with a time delay. In addition, the forward Euler method and Runge-Kutta method of order 4 (RK-4) are also applied in the present research. Some significant properties, such as convergence, positivity, boundedness, and consistency, are explored, and the proposed scheme preserves all the mentioned properties. The theoretical validation is conducted on how NSFD outperforms other methods in emulating key aspects of the continuous model, such as positive solution, stability, and equilibrium about delay.Hence, the above analysis also shows some of the limitations of the conventional finite difference methods, such as forward Euler and RK-4 in simulating such critical behaviors. This becomes more apparent when using larger steps. This indicated that NSFD is beneficial in identifying the essential characteristics of the continuous model with higher accuracy than the traditional approaches.

Original languageEnglish
Pages (from-to)1419-1446
Number of pages28
JournalCMES - Computer Modeling in Engineering and Sciences
Volume141
Issue number2
DOIs
Publication statusPublished - 2024
Externally publishedYes

Keywords

  • Typhoid virus
  • consistency
  • delay epidemic model
  • global stability
  • stability

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