Antibacterial activity against enterococcus faecium, enterococcus faecalis and inhibitory activity of monoamine oxidase a & b by persea americana "avocado" seed extracts

N. D. NOGBOU, Z. T. MKHOMBO, M. T. OLIVIER, M. O. OGUNROMBI, R. B. MASEKO, A. M. MUSYOKI*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

This study reported various Persia americana seed extracts for the presence and total content of phytochemicals, antibacterial activity and inhibitory activity against monoamine oxidase (MAO) A & B enzymes. Phytochemical studies showed that phenols, flavonoids and tannins were found in all the polar solvents. The highest antibacterial activity was exhibited against Gram-positive bacteria by acetone extract on Enterococcus faecium and methanol extract on Enterococcus faecalis. From the monoamine inhibition experiments, a significant inhibitory activity was observed from ethanolic extracts against MAO-A and from n-hexane extracts against MAO-B. This study demonstrates the antimicrobial activity of P. americana seed extracts against enterococci bacteria, E. faecium and E. faecalis. This finding offers hope of a potential new antibacterial compound in the treatment of these multidrug resistant bacteria.

Original languageEnglish
Pages (from-to)2093-2098
Number of pages6
JournalAsian Journal of Chemistry
Volume33
Issue number9
DOIs
Publication statusPublished - Sep 2021

Keywords

  • Antibacterial activity
  • Enterococcus faecalis
  • Enterococcus faecium
  • Persia americana

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