Antibacterial activity against enterococcus faecium, enterococcus faecalis and inhibitory activity of monoamine oxidase a & b by persea americana "avocado" seed extracts

This study reported various Persia americana seed extracts for the presence and total content of phytochemicals, antibacterial activity and inhibitory activity against monoamine oxidase (MAO) A & B enzymes. Phytochemical studies showed that phenols, flavonoids and tannins were found in all the polar solvents. The highest antibacterial activity was exhibited against Gram-positive bacteria by acetone extract on Enterococcus faecium and methanol extract on Enterococcus faecalis. From the monoamine inhibition experiments, a significant inhibitory activity was observed from ethanolic extracts against MAO-A and from n-hexane extracts against MAO-B. This study demonstrates the antimicrobial activity of P. americana seed extracts against enterococci bacteria, E. faecium and E. faecalis. This finding offers hope of a potential new antibacterial compound in the treatment of these multidrug resistant bacteria.