Antimicrobial utilization research and activities in Botswana, the past, present and the future

Celda Tiroyakgosi, Matshediso Matome, Joyce Kgatlwane, Bene D. Anand Paramadhas, Brighid Malone, Pinkie Mpinda-Joseph, Godfrey Mutashambara Rwegerera, Keamogetse Maika, Yohana Mashalla, Brian Godman*, Amos Massele

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A number of activities are ongoing to reduce AMR in Botswana by improving antimicrobial utilization across all sectors. However, there is a need to share experiences. With the objective of sharing these, the second one day symposium was held in the University of Botswana in October 2018 involving both private and public hospitals. In Lenmed Bokamoso hospital, ESKAPE organisms were associated with 50-90% of clinical infections; however, there was no correlation between healthcare associated infections (HAIs) and admission swab positivity with ESKAPE or ESBL isolates. Hang times, the time between a prescription and IV administration, were also discussed. At Nyangabwe Hospital, the prevalence of HAIs was 13.54%, 48.9% were laboratory confirmed of which 8.5% were blood stream infections (BSIs). The prevalence of different bacteria causing neonatal BSIs was also investigated. At Princess Marina Hospital, positive cultures were seen in 22.4% of blood cultures with contaminants comprising the majority. Several activities are ongoing in Botswana across sectors as a result of the findings and will be periodically reported to further improve antibiotic utilization.

Original languageEnglish
Pages (from-to)759-762
Number of pages4
JournalExpert Review of Anti-Infective Therapy
Issue number10
Publication statusPublished - 3 Oct 2019


  • Antimicrobials
  • Botswana
  • HAIs
  • blood stream infections
  • hang times


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