Chronic obstructive pulmonary disease: An update

Natalie Schellack, Gustav Schellack, Richard Omoding

Research output: Contribution to journalLiterature reviewpeer-review

1 Citation (Scopus)


© 2015 Medpharm. Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. It is a chronic condition that affects the respiratory system and worsens over time. The two major risks that are associated with this disease are cigarette smoking and an advancing age. It is concerning that the global incidence of this chronic illness is on the rise, with current projections indicating that it will become the third-leading cause of death by the year 2020. Inflammatory changes underlie the pathophysiology of COPD, with irreversible damage and a progressive narrowing of the air passages that follow. COPD is characterised by a progressive loss of lung function. In addition, the Global Strategy for the Diagnosis, Management, and Disease Prevention of Chronic Obstructive Pulmonary Disease, or GOLD, released the latest update of their Global Strategy for the Diagnosis, Management, and prevention of Chronic Obstructive Pulmonary Disease in 2015. This article provides an overview of the causative risk factors, the underlying disease process and pathophysiological changes, the classification and the management of COPD, including the latest perspectives on this highly-prevalent condition.
Original languageEnglish
Pages (from-to)24-29
Number of pages6
JournalSA Pharmaceutical Journal
Publication statusPublished - 1 Jan 2015


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