Compliance with South Africa’s Antimicrobial Resistance National Strategy Framework: are we there yet?

Deirdré Engler*, Johanna C. Meyer, Natalie Schellack, Amanj Kurdi, Brian Godman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Antimicrobial resistance (AMR) is a growing problem worldwide. South Africa has recently released its Antimicrobial Resistance National Strategy Framework (referred to as the Framework) to instigate antimicrobial stewardship programmes (ASPs). Consequently, there is a need to assess compliance with the Framework. Methods: Descriptive study design, collecting quantitative data, among pre-selected public healthcare facilities. One healthcare professional from each participating facility, involved in ASPs, was invited to participate. Results: Overall 26 facilities from 8 provinces participated. Average compliance to the Framework was 59.5% for the 26 facilities, with 38.0% for community health centres, 66.9% for referral hospitals and 73.5% for national central hospitals. For 7 facilities compliance was <50% while 5 facilities were >80% compliant. Conclusion: Although some facilities complied well with the Framework, overall compliance was sub-optimal. With the introduction of universal healthcare in South Africa, coupled with growing AMR rates, ongoing initiatives to actively implement the Framework should be targeted at non-compliant facilities.

Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalJournal of Chemotherapy
Publication statusPublished - 2020


  • South Africa
  • antimicrobial resistance
  • antimicrobial stewardship
  • compliance
  • framework
  • healthcare centres
  • hospitals


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