TY - JOUR
T1 - Diffuse infiltrative CD8+ lymphocytosis syndrome
T2 - review of the literature and report of a case.
AU - Feller, L.
AU - White, J. P.
AU - Bouckaert, M.
AU - Muthuphei, M. N.
PY - 2007/8
Y1 - 2007/8
N2 - Diffuse infiltrative lymphocytosis syndrome (DILS) is an uncommon manifestation of HIV infection characterised by persistent circulating CD8+ lymphocytosis accompanied by visceral lymphocytic infiltration. The lungs and the salivary glands are the most common organs involved. Parotid enlargement in HIV-seropositive subjects may represent HIV-associated lymphoepithelial lesions, hyperplastic lymphadenopathy, lymphoma, bacterial and viral infections, Sjögren's syndrome and DILS. Therefore confirmatory histopathological diagnosis and immunohistochemical analysis following a biopsy is essential to determine the exact nature of the salivary gland enlargement. A review of the literature of DILS and a description of a typical case of bilateral cystic lymphoepithelial lesions of the parotid glands, in an HIV-seropositive subject with DILS, is presented.
AB - Diffuse infiltrative lymphocytosis syndrome (DILS) is an uncommon manifestation of HIV infection characterised by persistent circulating CD8+ lymphocytosis accompanied by visceral lymphocytic infiltration. The lungs and the salivary glands are the most common organs involved. Parotid enlargement in HIV-seropositive subjects may represent HIV-associated lymphoepithelial lesions, hyperplastic lymphadenopathy, lymphoma, bacterial and viral infections, Sjögren's syndrome and DILS. Therefore confirmatory histopathological diagnosis and immunohistochemical analysis following a biopsy is essential to determine the exact nature of the salivary gland enlargement. A review of the literature of DILS and a description of a typical case of bilateral cystic lymphoepithelial lesions of the parotid glands, in an HIV-seropositive subject with DILS, is presented.
UR - http://www.scopus.com/inward/record.url?scp=38449101588&partnerID=8YFLogxK
M3 - Review article
C2 - 18019812
AN - SCOPUS:38449101588
SN - 1029-4864
VL - 62
SP - 314
EP - 317
JO - SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging
JF - SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging
IS - 7
ER -
