Diffuse infiltrative CD8+ lymphocytosis syndrome: review of the literature and report of a case.

L. Feller; J. P. White; M. Bouckaert; M. N. Muthuphei

Diffuse infiltrative CD8+ lymphocytosis syndrome: review of the literature and report of a case.

L. Feller^*
, J. P. White
, M. Bouckaert
, M. N. Muthuphei

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

9 Citations (Scopus)

Abstract

Diffuse infiltrative lymphocytosis syndrome (DILS) is an uncommon manifestation of HIV infection characterised by persistent circulating CD8+ lymphocytosis accompanied by visceral lymphocytic infiltration. The lungs and the salivary glands are the most common organs involved. Parotid enlargement in HIV-seropositive subjects may represent HIV-associated lymphoepithelial lesions, hyperplastic lymphadenopathy, lymphoma, bacterial and viral infections, Sjögren's syndrome and DILS. Therefore confirmatory histopathological diagnosis and immunohistochemical analysis following a biopsy is essential to determine the exact nature of the salivary gland enlargement. A review of the literature of DILS and a description of a typical case of bilateral cystic lymphoepithelial lesions of the parotid glands, in an HIV-seropositive subject with DILS, is presented.

Original language	English
Pages (from-to)	314-317
Number of pages	4
Journal	SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging
Volume	62
Issue number	7
Publication status	Published - Aug 2007
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

@article{ac8b7af43fe942508e9a4e935a60eef5,

title = "Diffuse infiltrative CD8+ lymphocytosis syndrome: review of the literature and report of a case.",

abstract = "Diffuse infiltrative lymphocytosis syndrome (DILS) is an uncommon manifestation of HIV infection characterised by persistent circulating CD8+ lymphocytosis accompanied by visceral lymphocytic infiltration. The lungs and the salivary glands are the most common organs involved. Parotid enlargement in HIV-seropositive subjects may represent HIV-associated lymphoepithelial lesions, hyperplastic lymphadenopathy, lymphoma, bacterial and viral infections, Sj{\"o}gren's syndrome and DILS. Therefore confirmatory histopathological diagnosis and immunohistochemical analysis following a biopsy is essential to determine the exact nature of the salivary gland enlargement. A review of the literature of DILS and a description of a typical case of bilateral cystic lymphoepithelial lesions of the parotid glands, in an HIV-seropositive subject with DILS, is presented.",

author = "L. Feller and White, \{J. P.\} and M. Bouckaert and Muthuphei, \{M. N.\}",

year = "2007",

month = aug,

language = "English",

volume = "62",

pages = "314--317",

journal = "SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging",

issn = "1029-4864",

publisher = "African Medical Association",

number = "7",

}

Diffuse infiltrative CD8+ lymphocytosis syndrome: review of the literature and report of a case. / Feller, L.; White, J. P.; Bouckaert, M. et al.
In: SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, Vol. 62, No. 7, 08.2007, p. 314-317.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Diffuse infiltrative CD8+ lymphocytosis syndrome

T2 - review of the literature and report of a case.

AU - Feller, L.

AU - White, J. P.

AU - Bouckaert, M.

AU - Muthuphei, M. N.

PY - 2007/8

Y1 - 2007/8

N2 - Diffuse infiltrative lymphocytosis syndrome (DILS) is an uncommon manifestation of HIV infection characterised by persistent circulating CD8+ lymphocytosis accompanied by visceral lymphocytic infiltration. The lungs and the salivary glands are the most common organs involved. Parotid enlargement in HIV-seropositive subjects may represent HIV-associated lymphoepithelial lesions, hyperplastic lymphadenopathy, lymphoma, bacterial and viral infections, Sjögren's syndrome and DILS. Therefore confirmatory histopathological diagnosis and immunohistochemical analysis following a biopsy is essential to determine the exact nature of the salivary gland enlargement. A review of the literature of DILS and a description of a typical case of bilateral cystic lymphoepithelial lesions of the parotid glands, in an HIV-seropositive subject with DILS, is presented.

AB - Diffuse infiltrative lymphocytosis syndrome (DILS) is an uncommon manifestation of HIV infection characterised by persistent circulating CD8+ lymphocytosis accompanied by visceral lymphocytic infiltration. The lungs and the salivary glands are the most common organs involved. Parotid enlargement in HIV-seropositive subjects may represent HIV-associated lymphoepithelial lesions, hyperplastic lymphadenopathy, lymphoma, bacterial and viral infections, Sjögren's syndrome and DILS. Therefore confirmatory histopathological diagnosis and immunohistochemical analysis following a biopsy is essential to determine the exact nature of the salivary gland enlargement. A review of the literature of DILS and a description of a typical case of bilateral cystic lymphoepithelial lesions of the parotid glands, in an HIV-seropositive subject with DILS, is presented.

UR - https://www.scopus.com/pages/publications/38449101588

M3 - Review article

C2 - 18019812

AN - SCOPUS:38449101588

SN - 1029-4864

VL - 62

SP - 314

EP - 317

JO - SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging

JF - SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging

IS - 7

ER -

Diffuse infiltrative CD8+ lymphocytosis syndrome: review of the literature and report of a case.

Abstract

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