Electrospun PCL-Based Materials for Health-Care Applications: An Overview

Teboho Clement Mokhena, Mandla Brian Chabalala, Sivuyisiwe Mapukata, Asanda Mtibe*, Lerato Hlekelele, Zamani Cele, Mokgaotsa Jonas Mochane, Bulelwa Ntsendwana, Toitoi Amos Nhlapo, Teboho Patrick Mokoena, Mokae Fanuel Bambo, Kgabo Phillemon Matabola, Suprakas Sinha Ray, Emmanuel Rotimi Sadiku, Katekani Shingange

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL-based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

Original languageEnglish
JournalMacromolecular Materials and Engineering
DOIs
Publication statusAccepted/In press - 2024

Keywords

  • biomedical applications
  • blends
  • composites
  • polycaprolactone

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