Epidemiology of rotavirus infection in North-western Nigeria

Maryam Aminu; A. A. Ahmad; J. U. Umoh; J. Dewar; M. D. Esona; A. D. Steele

doi:10.1093/tropej/fmn021

Epidemiology of rotavirus infection in North-western Nigeria

Maryam Aminu^*, A. A. Ahmad, J. U. Umoh, J. Dewar, M. D. Esona, A. D. Steele

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Rotaviruses (RV) are associated with ∼33 000 deaths in children <5 years of age annually in Nigeria. However, limited data exit on RV infection in north-western Nigeria. During July 2002 to July 2004, 1063 (869 diarrhoeic and 194 control) stool samples were collected from children <5 years of age presenting with diarrhoea in north-western Nigeria. The stools were analysed for RV antigen and further characterized by antigenic and genomic methods. RV was detected in 18% of children with diarrhoea and 7.2% of the age-matched case controls. The highest RV burden was detected in children <6-months-old. Long electropherotypes and VP6 subgroup I + II specificity predominated.

Original language	English
Pages (from-to)	340-342
Number of pages	3
Journal	Journal of Tropical Pediatrics
Volume	54
Issue number	5
DOIs	https://doi.org/10.1093/tropej/fmn021
Publication status	Published - Oct 2008
Externally published	Yes

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title = "Epidemiology of rotavirus infection in North-western Nigeria",

abstract = "Rotaviruses (RV) are associated with ∼33 000 deaths in children <5 years of age annually in Nigeria. However, limited data exit on RV infection in north-western Nigeria. During July 2002 to July 2004, 1063 (869 diarrhoeic and 194 control) stool samples were collected from children <5 years of age presenting with diarrhoea in north-western Nigeria. The stools were analysed for RV antigen and further characterized by antigenic and genomic methods. RV was detected in 18% of children with diarrhoea and 7.2% of the age-matched case controls. The highest RV burden was detected in children <6-months-old. Long electropherotypes and VP6 subgroup I + II specificity predominated.",

author = "Maryam Aminu and Ahmad, {A. A.} and Umoh, {J. U.} and J. Dewar and Esona, {M. D.} and Steele, {A. D.}",

note = "Funding Information: This study was conducted, thanks to the grant from UNESCO-L{\textquoteright}OR{\'E}AL Fellowship for Women in Life Sciences awarded to Dr M. Aminu The World Health Organization and the Medical Research Council of South Africa also supported the research.",

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AU - Aminu, Maryam

AU - Ahmad, A. A.

AU - Umoh, J. U.

AU - Dewar, J.

AU - Esona, M. D.

AU - Steele, A. D.

N1 - Funding Information: This study was conducted, thanks to the grant from UNESCO-L’ORÉAL Fellowship for Women in Life Sciences awarded to Dr M. Aminu The World Health Organization and the Medical Research Council of South Africa also supported the research.

PY - 2008/10

Y1 - 2008/10

N2 - Rotaviruses (RV) are associated with ∼33 000 deaths in children <5 years of age annually in Nigeria. However, limited data exit on RV infection in north-western Nigeria. During July 2002 to July 2004, 1063 (869 diarrhoeic and 194 control) stool samples were collected from children <5 years of age presenting with diarrhoea in north-western Nigeria. The stools were analysed for RV antigen and further characterized by antigenic and genomic methods. RV was detected in 18% of children with diarrhoea and 7.2% of the age-matched case controls. The highest RV burden was detected in children <6-months-old. Long electropherotypes and VP6 subgroup I + II specificity predominated.

AB - Rotaviruses (RV) are associated with ∼33 000 deaths in children <5 years of age annually in Nigeria. However, limited data exit on RV infection in north-western Nigeria. During July 2002 to July 2004, 1063 (869 diarrhoeic and 194 control) stool samples were collected from children <5 years of age presenting with diarrhoea in north-western Nigeria. The stools were analysed for RV antigen and further characterized by antigenic and genomic methods. RV was detected in 18% of children with diarrhoea and 7.2% of the age-matched case controls. The highest RV burden was detected in children <6-months-old. Long electropherotypes and VP6 subgroup I + II specificity predominated.

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JO - Journal of Tropical Pediatrics

JF - Journal of Tropical Pediatrics

IS - 5

ER -

Epidemiology of rotavirus infection in North-western Nigeria

Abstract

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