TY - JOUR
T1 - Experience with developing antibiotic stewardship programs in Serbia
T2 - Potential model for other Balkan countries?
AU - Kalaba, Marija
AU - Kosutic, Jovan
AU - Godman, Brian
AU - Radonjic, Vesela
AU - Vujic, Ana
AU - Jankovic, Slobodan
AU - Srebro, Dragana
AU - Kalaba, Zlatko
AU - Stojanovic, Radan
AU - Prostran, Milica
N1 - Publisher Copyright:
© 2018 2018 Future Medicine Ltd.
PY - 2018/3
Y1 - 2018/3
N2 - Aim: Antimicrobial resistance and inappropriate use of antibiotics in children are important issues. Consequently, there is a need to develop comprehensive stewardship programs even in hospitals with limited resources starting with children's hospitals. Methods: Retrospective observational analysis of antimicrobial utilization and resistance patterns over 5 years in a tertiary care children's hospital in Serbia. Results: Cumulative antimicrobial resistance decreased but was still high, with high cumulative resistance rates among the most widely used antibiotics in the hospital. Total antibiotic use decreased from 2010 to 2014 although there was still high prescribing of reserved antibiotics. Conclusion: Concerns with inappropriate use and high resistance rates among some antibiotics used in the hospital are being used to develop guidance on future antibiotic use in this hospital, building on the recently introduced antibiotic stewardship program, as well as encourage other hospitals in Serbia to review their policies.
AB - Aim: Antimicrobial resistance and inappropriate use of antibiotics in children are important issues. Consequently, there is a need to develop comprehensive stewardship programs even in hospitals with limited resources starting with children's hospitals. Methods: Retrospective observational analysis of antimicrobial utilization and resistance patterns over 5 years in a tertiary care children's hospital in Serbia. Results: Cumulative antimicrobial resistance decreased but was still high, with high cumulative resistance rates among the most widely used antibiotics in the hospital. Total antibiotic use decreased from 2010 to 2014 although there was still high prescribing of reserved antibiotics. Conclusion: Concerns with inappropriate use and high resistance rates among some antibiotics used in the hospital are being used to develop guidance on future antibiotic use in this hospital, building on the recently introduced antibiotic stewardship program, as well as encourage other hospitals in Serbia to review their policies.
KW - Serbia
KW - antibiotic resistance
KW - antibiotic utilization
KW - children
KW - hospitals
KW - low resource settings
KW - stewardship programs
UR - http://www.scopus.com/inward/record.url?scp=85044003918&partnerID=8YFLogxK
U2 - 10.2217/cer-2017-0055
DO - 10.2217/cer-2017-0055
M3 - Article
C2 - 29465263
AN - SCOPUS:85044003918
SN - 2042-6305
VL - 7
SP - 247
EP - 258
JO - Journal of Comparative Effectiveness Research
JF - Journal of Comparative Effectiveness Research
IS - 3
ER -
