TY - JOUR
T1 - Extramedullary myeloma in an HIV-seropositive subject. literature review and report of an unusual case
AU - Feller, Liviu
AU - White, Jason
AU - Wood, Neil H.
AU - Bouckaert, Michael
AU - Lemmer, Johan
AU - Raubenheimer, Erich J.
PY - 2009
Y1 - 2009
N2 - Myeloma is characterized by monoclonal bone marrow plasmacytosis, the presence of M-protein in serum and/or in urine and osteolytic bone lesions. HIV-seropositive subjects with myeloma are younger at the time of diagnosis of the tumour and usually the myeloma has a more aggressive clinical course than it does in HIV-seronegative subjects. A case of an HIV-seropositive woman in whom myeloma was diagnosed following progressive swelling of the face, is reported. In addition to bone marrow plasmacytosis and the presence of M-protein in the serum, the patient had an extramedullary lesion affecting the oral cavity, maxilla, parotid gland and paranasal sinuses, and extending intracranially and intraorbitally.
AB - Myeloma is characterized by monoclonal bone marrow plasmacytosis, the presence of M-protein in serum and/or in urine and osteolytic bone lesions. HIV-seropositive subjects with myeloma are younger at the time of diagnosis of the tumour and usually the myeloma has a more aggressive clinical course than it does in HIV-seronegative subjects. A case of an HIV-seropositive woman in whom myeloma was diagnosed following progressive swelling of the face, is reported. In addition to bone marrow plasmacytosis and the presence of M-protein in the serum, the patient had an extramedullary lesion affecting the oral cavity, maxilla, parotid gland and paranasal sinuses, and extending intracranially and intraorbitally.
UR - http://www.scopus.com/inward/record.url?scp=61849139588&partnerID=8YFLogxK
U2 - 10.1186/1746-160X-5-4
DO - 10.1186/1746-160X-5-4
M3 - Article
C2 - 19152712
AN - SCOPUS:61849139588
SN - 1746-160X
VL - 5
JO - Head and Face Medicine
JF - Head and Face Medicine
IS - 1
M1 - 4
ER -
