Gastro-oesophageal reflux: An overview of the pharmacotherapeutic treatment options

L. Malan, Q. Labuschagne, N. Schellack*, G. Schellack, J. C. Meyer

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Gastro-oesophageal reflux disease (GORD) produces symptoms that cause great irritation to the patient. Pharmacotherapeutic management is directed at minimising these symptoms and reducing the causative factors, e.g. acid production, thereby providing relief. Currently available agents include simple antacids and acid suppression therapy, including histamine 2-receptor antagonists, proton pump inhibitors, mucosal or cytoprotective agents and pro-motility agents. Deciding on appropriate therapy will depend on the diagnosis, side-effects and cost-effectiveness of the treatment

Original languageEnglish
Pages (from-to)31-36
Number of pages6
JournalSA Pharmaceutical Journal
Volume84
Issue number1
Publication statusPublished - 2017

Keywords

  • GORD
  • Gastro-oesophageal reflux
  • PPIs
  • Proton-pump inhibitors

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