TY - JOUR
T1 - Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa
AU - Afolabi, Kayode O.
AU - Iweriebor, Benson Chucks
AU - Okoh, Anthony I.
AU - Obi, Larry C.
N1 - Funding Information:
The authors acknowledge the National Research Foundation (NRF), South African Medical Research Council (SAMRC), and Govan Mbeki Research and Development Centre (GMRDC) of University of Fort Hare for their financial supports.
Publisher Copyright:
© 2017 Kayode O. Afolabi et al.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - © 2017 Kayode O. Afolabi et al. Globally, Porcine circovirus type 2 (PCV2) is a recognized viral pathogen of great economic value in pig farming. It is the major cause of ravaging postweaning multisystemic wasting syndrome (PMWS) and many other disease syndromes generally regarded as Porcine circovirus associated diseases (PCVAD) in Europe. PCV2 infections, specifically PMWS, had impacted huge economic loss on swine production at different regions of the world. It has been studied and reported at different parts of the globe including: North and South America, Europe, Asia, Oceania, Middle East, and the Caribbean. However, till date, this virus and its associated diseases have been grossly understudied in sub-Sahara African region and the entire continent at large. Two out of forty-nine, representing just about 4% of countries that make up sub-Sahara Africa presently, have limited records on reported cases and occurrence of the viral pathogen despite the ubiquitous nature of the virus. This review presents an overview of the discovery of Porcine circovirus and its associated diseases in global pig herds and emphasizes the latest trends in PCV2 vaccines and antiviral drugs development and the information gaps that exist on the occurrence of this important viral pathogen in swine herds of sub-Saharan Africa countries. This will serve as wake-up call for immediate and relevant actions by stakeholders in the region.
AB - © 2017 Kayode O. Afolabi et al. Globally, Porcine circovirus type 2 (PCV2) is a recognized viral pathogen of great economic value in pig farming. It is the major cause of ravaging postweaning multisystemic wasting syndrome (PMWS) and many other disease syndromes generally regarded as Porcine circovirus associated diseases (PCVAD) in Europe. PCV2 infections, specifically PMWS, had impacted huge economic loss on swine production at different regions of the world. It has been studied and reported at different parts of the globe including: North and South America, Europe, Asia, Oceania, Middle East, and the Caribbean. However, till date, this virus and its associated diseases have been grossly understudied in sub-Sahara African region and the entire continent at large. Two out of forty-nine, representing just about 4% of countries that make up sub-Sahara Africa presently, have limited records on reported cases and occurrence of the viral pathogen despite the ubiquitous nature of the virus. This review presents an overview of the discovery of Porcine circovirus and its associated diseases in global pig herds and emphasizes the latest trends in PCV2 vaccines and antiviral drugs development and the information gaps that exist on the occurrence of this important viral pathogen in swine herds of sub-Saharan Africa countries. This will serve as wake-up call for immediate and relevant actions by stakeholders in the region.
UR - http://www.scopus.com/inward/record.url?scp=85016574522&partnerID=8YFLogxK
U2 - 10.1155/2017/6807964
DO - 10.1155/2017/6807964
M3 - Literature review
C2 - 28386278
SN - 1687-8639
VL - 2017
JO - Advances in Virology
JF - Advances in Virology
M1 - 6807964
ER -