Health equity and the usage of atypical antipsychotics within the Brazilian national health system: findings and implications

Isabella de Figueiredo Zuppo*, Cristina Mariano Ruas, Helian Nunes de Oliveira, Brian Godman, Saulo Castel, Milton L. Wainberg, Edna Afonso Reis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: There is a need to evaluate the health equity of atypical antipsychotics users who obtain their medicines from the Brazilian National Health System (SUS) through the identification of key factors that influence their health status due to concerns with equity of care. Research design and methods: Cross-sectional study among patients attending state pharmacies in Brazil. Individuals were included if they used atypical antipsychotics, aged ≥18 years, and answered the EQ-5D-3 L questionnaire. Sociodemographic, behavioral, and clinical data were collected. The dependent variable was health status. Associations between the independent variables and the dependent variable were analyzed by adjusting a linear regression model. Results: Overall, 388 individuals met the eligibility criteria and were included in the analysis. The final multiple linear regression model demonstrated a statistically significant association between VAS and suicide attempts, private care, current antipsychotics, comorbidities, and perceived family support. Expert Commentary: The study identified several factors both individual and collective that correlate with the health status of atypical antipsychotic users and confirmed the importance of providing medicines for treating psychotic disorders. However, other factors are involved including social support. Our results suggest additional activities and policies are necessary including strategies to address the differences in private and public health care.

Original languageEnglish
Pages (from-to)743-751
Number of pages9
JournalExpert Review of Pharmacoeconomics and Outcomes Research
Issue number4
Publication statusPublished - 2021


  • Antipsychotic agents
  • health equity
  • health status disparities
  • psychotic disorders
  • schizophrenia spectrum and other psychotic disorders


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