HIV-associated oral Kaposi sarcoma and HHV-8: a review.

Liviu Feller; Johan Lemmer; Neil H. Wood; Yusuf Jadwat; Erich J. Raubenheimer

HIV-associated oral Kaposi sarcoma and HHV-8: a review.

Liviu Feller^*, Johan Lemmer, Neil H. Wood, Yusuf Jadwat, Erich J. Raubenheimer

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

20 Citations (Scopus)

Abstract

Kaposi sarcoma is the most common malignant tumour associated with HIV infection. In the majority of cases oral tissues are involved and in 22% the initial presentation is in the oral cavity. The oral lesions are either single or multifocal, and the palate, gingiva and tongue are the sites most frequently involved. The pathogenesis of Kaposi sarcoma in HIV-seropositive subjects is complex. It involves interaction between human herpesvirus-8 (HHV-8) and HIV, altered cellular signal transduction pathways, and increased production of cytokines and growth factors. The multifactorial nature and clinical stages in the growth of oral Kaposi sarcoma are discussed.

Original language	English
Pages (from-to)	129-136
Number of pages	8
Journal	Journal of the International Academy of Periodontology
Volume	9
Issue number	4
Publication status	Published - Oct 2007
Externally published	Yes

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Cite this

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title = "HIV-associated oral Kaposi sarcoma and HHV-8: a review.",

abstract = "Kaposi sarcoma is the most common malignant tumour associated with HIV infection. In the majority of cases oral tissues are involved and in 22% the initial presentation is in the oral cavity. The oral lesions are either single or multifocal, and the palate, gingiva and tongue are the sites most frequently involved. The pathogenesis of Kaposi sarcoma in HIV-seropositive subjects is complex. It involves interaction between human herpesvirus-8 (HHV-8) and HIV, altered cellular signal transduction pathways, and increased production of cytokines and growth factors. The multifactorial nature and clinical stages in the growth of oral Kaposi sarcoma are discussed.",

author = "Liviu Feller and Johan Lemmer and Wood, {Neil H.} and Yusuf Jadwat and Raubenheimer, {Erich J.}",

year = "2007",

month = oct,

language = "English",

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pages = "129--136",

journal = "Journal of the International Academy of Periodontology",

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TY - JOUR

T1 - HIV-associated oral Kaposi sarcoma and HHV-8

T2 - a review.

AU - Feller, Liviu

AU - Lemmer, Johan

AU - Wood, Neil H.

AU - Jadwat, Yusuf

AU - Raubenheimer, Erich J.

PY - 2007/10

Y1 - 2007/10

N2 - Kaposi sarcoma is the most common malignant tumour associated with HIV infection. In the majority of cases oral tissues are involved and in 22% the initial presentation is in the oral cavity. The oral lesions are either single or multifocal, and the palate, gingiva and tongue are the sites most frequently involved. The pathogenesis of Kaposi sarcoma in HIV-seropositive subjects is complex. It involves interaction between human herpesvirus-8 (HHV-8) and HIV, altered cellular signal transduction pathways, and increased production of cytokines and growth factors. The multifactorial nature and clinical stages in the growth of oral Kaposi sarcoma are discussed.

AB - Kaposi sarcoma is the most common malignant tumour associated with HIV infection. In the majority of cases oral tissues are involved and in 22% the initial presentation is in the oral cavity. The oral lesions are either single or multifocal, and the palate, gingiva and tongue are the sites most frequently involved. The pathogenesis of Kaposi sarcoma in HIV-seropositive subjects is complex. It involves interaction between human herpesvirus-8 (HHV-8) and HIV, altered cellular signal transduction pathways, and increased production of cytokines and growth factors. The multifactorial nature and clinical stages in the growth of oral Kaposi sarcoma are discussed.

UR - http://www.scopus.com/inward/record.url?scp=38449112734&partnerID=8YFLogxK

M3 - Review article

C2 - 17987883

AN - SCOPUS:38449112734

SN - 1466-2094

VL - 9

SP - 129

EP - 136

JO - Journal of the International Academy of Periodontology

JF - Journal of the International Academy of Periodontology

IS - 4

ER -

HIV-associated oral Kaposi sarcoma and HHV-8: a review.

Abstract

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