HIV infection and HIV-1 clades among pregnant women in Harare, Zimbabwe

C. L. Obi*, H. P. McAdoo, M. Murray, S. A. Tswana, S. R. Moyo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Objective: To determine HIV-1 seropositivity and HIV-1 clades/subtypes among pregnant women attending different clinics in Harare, Zimbabwe. Design: A prospective study. Subjects: 206 pregnant women attending Edith Opperman and Budiriro clinics in Harare. Main Outcome Measures: Frequency distribution of the various HIV-1 clades and rate of HIV-1 seropositivity. Results: Results obtained showed that out of the 206 pregnant women screened, 60 (29.1%) were HIV-1 seropositive. The most predominant clade was HIV-1 clade C (66.6%) whereas HIV-1 clades A and B accounted for 48.3% and 33.3% of HIV-1 clades respectively. Results also revealed dual infections with clades A and C (45%), A and D (10%), B and C (30%) and multiple infections with A, B, C and D (6.6%) whereas two (3.3%) were non-reactive. Conclusion: Finally, the data on HIV-1 clades are of immense immunological, molecular and epidemiological importance in Harare, Zimbabwe and should serve as base line data for future investigations in the country.

Original languageEnglish
Pages (from-to)188-192
Number of pages5
JournalCentral African Journal of Medicine
Issue number7
Publication statusPublished - Jul 1997
Externally publishedYes


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