HIV infection and HIV-1 clades among pregnant women in Harare, Zimbabwe

C. L. Obi; H. P. McAdoo; M. Murray; S. A. Tswana; S. R. Moyo

HIV infection and HIV-1 clades among pregnant women in Harare, Zimbabwe

C. L. Obi^*
, H. P. McAdoo
, M. Murray
, S. A. Tswana
, S. R. Moyo

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Objective: To determine HIV-1 seropositivity and HIV-1 clades/subtypes among pregnant women attending different clinics in Harare, Zimbabwe. Design: A prospective study. Subjects: 206 pregnant women attending Edith Opperman and Budiriro clinics in Harare. Main Outcome Measures: Frequency distribution of the various HIV-1 clades and rate of HIV-1 seropositivity. Results: Results obtained showed that out of the 206 pregnant women screened, 60 (29.1%) were HIV-1 seropositive. The most predominant clade was HIV-1 clade C (66.6%) whereas HIV-1 clades A and B accounted for 48.3% and 33.3% of HIV-1 clades respectively. Results also revealed dual infections with clades A and C (45%), A and D (10%), B and C (30%) and multiple infections with A, B, C and D (6.6%) whereas two (3.3%) were non-reactive. Conclusion: Finally, the data on HIV-1 clades are of immense immunological, molecular and epidemiological importance in Harare, Zimbabwe and should serve as base line data for future investigations in the country.

Original language	English
Pages (from-to)	188-192
Number of pages	5
Journal	Central African Journal of Medicine
Volume	43
Issue number	7
Publication status	Published - Jul 1997
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

@article{a88bd8916fbc453e87cb3ed6cee66036,

title = "HIV infection and HIV-1 clades among pregnant women in Harare, Zimbabwe",

abstract = "Objective: To determine HIV-1 seropositivity and HIV-1 clades/subtypes among pregnant women attending different clinics in Harare, Zimbabwe. Design: A prospective study. Subjects: 206 pregnant women attending Edith Opperman and Budiriro clinics in Harare. Main Outcome Measures: Frequency distribution of the various HIV-1 clades and rate of HIV-1 seropositivity. Results: Results obtained showed that out of the 206 pregnant women screened, 60 (29.1\%) were HIV-1 seropositive. The most predominant clade was HIV-1 clade C (66.6\%) whereas HIV-1 clades A and B accounted for 48.3\% and 33.3\% of HIV-1 clades respectively. Results also revealed dual infections with clades A and C (45\%), A and D (10\%), B and C (30\%) and multiple infections with A, B, C and D (6.6\%) whereas two (3.3\%) were non-reactive. Conclusion: Finally, the data on HIV-1 clades are of immense immunological, molecular and epidemiological importance in Harare, Zimbabwe and should serve as base line data for future investigations in the country.",

author = "Obi, \{C. L.\} and McAdoo, \{H. P.\} and M. Murray and Tswana, \{S. A.\} and Moyo, \{S. R.\}",

year = "1997",

month = jul,

language = "English",

volume = "43",

pages = "188--192",

journal = "Central African Journal of Medicine",

issn = "0008-9176",

publisher = "Central African Journal of Medicine Co.",

number = "7",

}

TY - JOUR

T1 - HIV infection and HIV-1 clades among pregnant women in Harare, Zimbabwe

AU - Obi, C. L.

AU - McAdoo, H. P.

AU - Murray, M.

AU - Tswana, S. A.

AU - Moyo, S. R.

PY - 1997/7

Y1 - 1997/7

N2 - Objective: To determine HIV-1 seropositivity and HIV-1 clades/subtypes among pregnant women attending different clinics in Harare, Zimbabwe. Design: A prospective study. Subjects: 206 pregnant women attending Edith Opperman and Budiriro clinics in Harare. Main Outcome Measures: Frequency distribution of the various HIV-1 clades and rate of HIV-1 seropositivity. Results: Results obtained showed that out of the 206 pregnant women screened, 60 (29.1%) were HIV-1 seropositive. The most predominant clade was HIV-1 clade C (66.6%) whereas HIV-1 clades A and B accounted for 48.3% and 33.3% of HIV-1 clades respectively. Results also revealed dual infections with clades A and C (45%), A and D (10%), B and C (30%) and multiple infections with A, B, C and D (6.6%) whereas two (3.3%) were non-reactive. Conclusion: Finally, the data on HIV-1 clades are of immense immunological, molecular and epidemiological importance in Harare, Zimbabwe and should serve as base line data for future investigations in the country.

AB - Objective: To determine HIV-1 seropositivity and HIV-1 clades/subtypes among pregnant women attending different clinics in Harare, Zimbabwe. Design: A prospective study. Subjects: 206 pregnant women attending Edith Opperman and Budiriro clinics in Harare. Main Outcome Measures: Frequency distribution of the various HIV-1 clades and rate of HIV-1 seropositivity. Results: Results obtained showed that out of the 206 pregnant women screened, 60 (29.1%) were HIV-1 seropositive. The most predominant clade was HIV-1 clade C (66.6%) whereas HIV-1 clades A and B accounted for 48.3% and 33.3% of HIV-1 clades respectively. Results also revealed dual infections with clades A and C (45%), A and D (10%), B and C (30%) and multiple infections with A, B, C and D (6.6%) whereas two (3.3%) were non-reactive. Conclusion: Finally, the data on HIV-1 clades are of immense immunological, molecular and epidemiological importance in Harare, Zimbabwe and should serve as base line data for future investigations in the country.

UR - https://www.scopus.com/pages/publications/0031174364

M3 - Article

C2 - 9431751

AN - SCOPUS:0031174364

SN - 0008-9176

VL - 43

SP - 188

EP - 192

JO - Central African Journal of Medicine

JF - Central African Journal of Medicine

IS - 7

ER -

HIV infection and HIV-1 clades among pregnant women in Harare, Zimbabwe

Abstract

UN SDGs

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