Hypertension: A review of antihypertensive medication

N. Schellack*, P. Naicker

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


This article provides an overview of the changes that have taken place in the diagnosis and management of hypertension over the past decade. Hypertension remains a very common condition seen in South Africa. The approach to the management of hypertension includes necessary lifestyle modifications and a decisive, stepwise escalation process in the pharmacotherapeutic management thereof. Thiazide diuretics are still being promoted by most guidelines to be the initial (first-line) drug of choice, with the addition of other suitable antihypertensive agents, if necessary, and according to any relevant comorbid conditions.

Original languageEnglish
Pages (from-to)20-27
Number of pages8
JournalSA Pharmaceutical Journal
Issue number5
Publication statusPublished - 1 Oct 2020


  • Angiotensin II-receptor blockers
  • Angiotensin-converting enzyme inhibitors
  • Antihypertensive agents
  • Calcium-channel blockers
  • Fixed-dose combination therapy
  • Hypertension


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