Identification of phytochemical constituents within the n-hexane leaf extract of Senna italica (Mill) using gas chromatography-mass spectrometry (GC-MS) analysis

Sechene Stanley Gololo*, Ntwanano Sipho Mapfumari, L. S. Sethoga, Mutendela Tabile Olivier, L. J. Shai, Mototelo Alfred Mogale

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

© 2016,Pharmainfo Publications. All rights reserved. Senna italica is widely used in traditional medicine for treatment of intestinal tumours and urinary tract infections. Both its leaves and roots were reported to possess antioxidant,antibacterial and anti-inflammatory activities. The leaves of Senna italica were extracted with n-hexane by cold maceration extraction procedure and the resultant extract was subjected to phytochemical analyses using GC-MS technique. Several compounds with known biological activities were detected and identified based on GC-MS data as Phytol (3,7,11,15-Tetramethyl-2-hexadecen-1-ol); 1,2-Benzenedicarboxylic acid,mono (2-ethylheptyl) ester; n-Tetracontane; 13-Docosenamide; Squalene (2,6,10,14,18,22-Hexamethyltetracosane),1-Heptacosanol; 1,2-Epoxynonadecane; α-Tocopherol-β-D-mannoside; Stigmasterol; γ-Sitosterol and Lupeol. The findings of the study support the usage of Senna italica in traditional medicinal as most of the identified compounds are known to possess biological activities.
Original languageEnglish
Pages (from-to)1141-1143
Number of pages3
JournalJournal of Pharmaceutical Sciences and Research
Volume8
Issue number10
Publication statusPublished - 1 Oct 2016

Keywords

  • Compound identification
  • GC-MS
  • N-hexane extract
  • Phytochemical constituents
  • Senna italica

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