TY - JOUR
T1 - Identification of phytochemical constituents within the n-hexane leaf extract of Senna italica (Mill) using gas chromatography-mass spectrometry (GC-MS) analysis
AU - Gololo, Sechene Stanley
AU - Mapfumari, Ntwanano Sipho
AU - Sethoga, L. S.
AU - Olivier, Mutendela Tabile
AU - Shai, L. J.
AU - Mogale, Mototelo Alfred
N1 - Publisher Copyright:
© 2016,Pharmainfo Publications. All rights reserved.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - © 2016,Pharmainfo Publications. All rights reserved. Senna italica is widely used in traditional medicine for treatment of intestinal tumours and urinary tract infections. Both its leaves and roots were reported to possess antioxidant,antibacterial and anti-inflammatory activities. The leaves of Senna italica were extracted with n-hexane by cold maceration extraction procedure and the resultant extract was subjected to phytochemical analyses using GC-MS technique. Several compounds with known biological activities were detected and identified based on GC-MS data as Phytol (3,7,11,15-Tetramethyl-2-hexadecen-1-ol); 1,2-Benzenedicarboxylic acid,mono (2-ethylheptyl) ester; n-Tetracontane; 13-Docosenamide; Squalene (2,6,10,14,18,22-Hexamethyltetracosane),1-Heptacosanol; 1,2-Epoxynonadecane; α-Tocopherol-β-D-mannoside; Stigmasterol; γ-Sitosterol and Lupeol. The findings of the study support the usage of Senna italica in traditional medicinal as most of the identified compounds are known to possess biological activities.
AB - © 2016,Pharmainfo Publications. All rights reserved. Senna italica is widely used in traditional medicine for treatment of intestinal tumours and urinary tract infections. Both its leaves and roots were reported to possess antioxidant,antibacterial and anti-inflammatory activities. The leaves of Senna italica were extracted with n-hexane by cold maceration extraction procedure and the resultant extract was subjected to phytochemical analyses using GC-MS technique. Several compounds with known biological activities were detected and identified based on GC-MS data as Phytol (3,7,11,15-Tetramethyl-2-hexadecen-1-ol); 1,2-Benzenedicarboxylic acid,mono (2-ethylheptyl) ester; n-Tetracontane; 13-Docosenamide; Squalene (2,6,10,14,18,22-Hexamethyltetracosane),1-Heptacosanol; 1,2-Epoxynonadecane; α-Tocopherol-β-D-mannoside; Stigmasterol; γ-Sitosterol and Lupeol. The findings of the study support the usage of Senna italica in traditional medicinal as most of the identified compounds are known to possess biological activities.
KW - Compound identification
KW - GC-MS
KW - N-hexane extract
KW - Phytochemical constituents
KW - Senna italica
UR - http://www.scopus.com/inward/record.url?scp=84992386961&partnerID=8YFLogxK
M3 - Article
SN - 0975-1459
VL - 8
SP - 1141
EP - 1143
JO - Journal of Pharmaceutical Sciences and Research
JF - Journal of Pharmaceutical Sciences and Research
IS - 10
ER -