In vitro antigonorrhea activity of the aerial part of asparagus suaveolens n-hexane fraction and palmitone as a bioactive compound

Mutendela Tabile Olivier, Freddy Munyololo Muganza*, Leshweni Jeremia Shai, Sechene Stanley Gololo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Asparagus suaveolens is a medicinal plant used in Lesotho and South Africa to treat epilepsy and gonorrhea. The current investigation identifies the compound responsible for the antiepileptic and antimicrobial properties as palmitone which showed antigonorrhea activities against WHO 2008 Neisseria gonorrhea F and O strains more than the standard used, gentamicin. These results support the traditional use of A. suaveolens for treatment of gonorrhea and epilepsy since palmitone is known as an anticonvulsant agent. This is the first study indicating the presence of palmitone in the Asparagus genus and demonstrates the in vitro antigonorrhea activity of palmitone.
Original languageEnglish
Pages (from-to)1319-1321
Number of pages3
JournalNatural Product Communications
Volume11
Issue number9
DOIs
Publication statusPublished - 1 Jan 2016

Keywords

  • Antigonorrhea
  • Asparagus suaveolens
  • Minimum inhibitory concentration
  • Palmitone

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