In vitro antigonorrhea activity of the aerial part of asparagus suaveolens n-hexane fraction and palmitone as a bioactive compound

Mutendela Tabile Olivier; Freddy Munyololo Muganza; Leshweni Jeremia Shai; Sechene Stanley Gololo

doi:10.1177/1934578x1601100935

In vitro antigonorrhea activity of the aerial part of asparagus suaveolens n-hexane fraction and palmitone as a bioactive compound

Mutendela Tabile Olivier, Freddy Munyololo Muganza^*, Leshweni Jeremia Shai, Sechene Stanley Gololo

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Asparagus suaveolens is a medicinal plant used in Lesotho and South Africa to treat epilepsy and gonorrhea. The current investigation identifies the compound responsible for the antiepileptic and antimicrobial properties as palmitone which showed antigonorrhea activities against WHO 2008 Neisseria gonorrhea F and O strains more than the standard used, gentamicin. These results support the traditional use of A. suaveolens for treatment of gonorrhea and epilepsy since palmitone is known as an anticonvulsant agent. This is the first study indicating the presence of palmitone in the Asparagus genus and demonstrates the in vitro antigonorrhea activity of palmitone.

Original language	English
Pages (from-to)	1319-1321
Number of pages	3
Journal	Natural Product Communications
Volume	11
Issue number	9
DOIs	https://doi.org/10.1177/1934578x1601100935
Publication status	Published - 1 Jan 2016

Keywords

Antigonorrhea
Asparagus suaveolens
Minimum inhibitory concentration
Palmitone

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/1934578x1601100935

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abstract = "Asparagus suaveolens is a medicinal plant used in Lesotho and South Africa to treat epilepsy and gonorrhea. The current investigation identifies the compound responsible for the antiepileptic and antimicrobial properties as palmitone which showed antigonorrhea activities against WHO 2008 Neisseria gonorrhea F and O strains more than the standard used, gentamicin. These results support the traditional use of A. suaveolens for treatment of gonorrhea and epilepsy since palmitone is known as an anticonvulsant agent. This is the first study indicating the presence of palmitone in the Asparagus genus and demonstrates the in vitro antigonorrhea activity of palmitone.",

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AU - Olivier, Mutendela Tabile

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AU - Shai, Leshweni Jeremia

AU - Gololo, Sechene Stanley

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N2 - Asparagus suaveolens is a medicinal plant used in Lesotho and South Africa to treat epilepsy and gonorrhea. The current investigation identifies the compound responsible for the antiepileptic and antimicrobial properties as palmitone which showed antigonorrhea activities against WHO 2008 Neisseria gonorrhea F and O strains more than the standard used, gentamicin. These results support the traditional use of A. suaveolens for treatment of gonorrhea and epilepsy since palmitone is known as an anticonvulsant agent. This is the first study indicating the presence of palmitone in the Asparagus genus and demonstrates the in vitro antigonorrhea activity of palmitone.

AB - Asparagus suaveolens is a medicinal plant used in Lesotho and South Africa to treat epilepsy and gonorrhea. The current investigation identifies the compound responsible for the antiepileptic and antimicrobial properties as palmitone which showed antigonorrhea activities against WHO 2008 Neisseria gonorrhea F and O strains more than the standard used, gentamicin. These results support the traditional use of A. suaveolens for treatment of gonorrhea and epilepsy since palmitone is known as an anticonvulsant agent. This is the first study indicating the presence of palmitone in the Asparagus genus and demonstrates the in vitro antigonorrhea activity of palmitone.

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In vitro antigonorrhea activity of the aerial part of asparagus suaveolens n-hexane fraction and palmitone as a bioactive compound

Abstract

Keywords

UN SDGs

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