Losses of vitamin A from a paediatric TPN lipid emulsion stored at 30°C under ward lighting and from an aqueous glucose/amino acid solution stored at 2-8°C in the dark were determined when different containers were used. Vitamin A assay was performed by reverse-phase HPLC. In the first instance, a PVC bag and a Buretrol showed little difference in t90% (20 days and > 21 days, respectively). In the second case, t90% in both a PVC bag and a glass container was ∼- 12 days. Hence, the material of the container has little effect on vitamin A stability in these two admixtures.
|Number of pages||3|
|Journal||International Journal of Pharmaceutics|
|Publication status||Published - 1 Feb 1991|
- Glass container
- PVC bag
- Vitamin A