Lamivudine monotherapy as a holding regimen in the era of antiretroviral treatment resistance

Johanna Catharina Meyer*, Natalie Schellack

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

© Medpharm. Limited treatment options are available for HIV-infected paediatric patients that are virologically failing combination antiretroviral treatment (cART). This paper describes the use of lamivudine monotherapy (LM) as a holding strategy for the short-term treatment of specific multi-drug resistant paediatric patients, where a definite suppressive cART regimen is not possible. Lamivudine monotherapy should only be used under close supervision and monitoring of an expert HIV clinician.
Original languageEnglish
Pages (from-to)43-45
Number of pages3
JournalSA Pharmaceutical Journal
Volume82
Issue number9
Publication statusPublished - 1 Jan 2015

Keywords

  • Holding regimen
  • Lamivudine monotherapy
  • Paediatric ART
  • Virological failure

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