Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient

Nthabiseng Ellen Mothata; Takalani Gidion Morulana; Nyaweleni Tshifularo; Phumudzo Bridgett Nemutaduni; Nozipho Elizabeth Nyakale; Moshawa Calvin Khaba

doi:10.1155/2021/6655491

Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient

Nthabiseng Ellen Mothata, Takalani Gidion Morulana, Nyaweleni Tshifularo, Phumudzo Bridgett Nemutaduni, Nozipho Elizabeth Nyakale, Moshawa Calvin Khaba^*

^*Corresponding author for this work

Anatomical Pathology

Research output: Contribution to journal › Article › peer-review

Abstract

Papillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. Although the disease is diagnosed at a later stage, the prognosis is favourable. When these patients present with lymph nodal and/or pulmonary metastases, they may be initially confused for infectious diseases such as tuberculosis. Therefore, thorough clinical assessment including radiology and microbiological and histopathological assessment is important for early and correct diagnosis. We report an 11-year-old female patient who presented with cervical lymphadenopathy and the histopathological assessment confirmed metastatic papillary thyroid carcinoma. Subsequent radiological investigation revealed further metastasis to the lung. This manuscript highlights the difficulties that might be encountered in the initial management of paediatric PTC which present atypically.

Original language	English
Article number	6655491
Journal	Case Reports in Endocrinology
Volume	2021
DOIs	https://doi.org/10.1155/2021/6655491
Publication status	Published - 2021

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title = "Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient",

abstract = "Papillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. Although the disease is diagnosed at a later stage, the prognosis is favourable. When these patients present with lymph nodal and/or pulmonary metastases, they may be initially confused for infectious diseases such as tuberculosis. Therefore, thorough clinical assessment including radiology and microbiological and histopathological assessment is important for early and correct diagnosis. We report an 11-year-old female patient who presented with cervical lymphadenopathy and the histopathological assessment confirmed metastatic papillary thyroid carcinoma. Subsequent radiological investigation revealed further metastasis to the lung. This manuscript highlights the difficulties that might be encountered in the initial management of paediatric PTC which present atypically.",

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AU - Mothata, Nthabiseng Ellen

AU - Morulana, Takalani Gidion

AU - Tshifularo, Nyaweleni

AU - Nemutaduni, Phumudzo Bridgett

AU - Nyakale, Nozipho Elizabeth

AU - Khaba, Moshawa Calvin

PY - 2021

Y1 - 2021

N2 - Papillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. Although the disease is diagnosed at a later stage, the prognosis is favourable. When these patients present with lymph nodal and/or pulmonary metastases, they may be initially confused for infectious diseases such as tuberculosis. Therefore, thorough clinical assessment including radiology and microbiological and histopathological assessment is important for early and correct diagnosis. We report an 11-year-old female patient who presented with cervical lymphadenopathy and the histopathological assessment confirmed metastatic papillary thyroid carcinoma. Subsequent radiological investigation revealed further metastasis to the lung. This manuscript highlights the difficulties that might be encountered in the initial management of paediatric PTC which present atypically.

AB - Papillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. Although the disease is diagnosed at a later stage, the prognosis is favourable. When these patients present with lymph nodal and/or pulmonary metastases, they may be initially confused for infectious diseases such as tuberculosis. Therefore, thorough clinical assessment including radiology and microbiological and histopathological assessment is important for early and correct diagnosis. We report an 11-year-old female patient who presented with cervical lymphadenopathy and the histopathological assessment confirmed metastatic papillary thyroid carcinoma. Subsequent radiological investigation revealed further metastasis to the lung. This manuscript highlights the difficulties that might be encountered in the initial management of paediatric PTC which present atypically.

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JO - Case Reports in Endocrinology

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Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient

Abstract

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