Novel human rotavirus of genotype G5P[6] identified in a stool specimen from a Chinese girl with diarrhea

Zhao Jun Duan*, Dan Di Li, Qing Zhang, Na Liu, Can Ping Huang, Xi Jiang, Baomin Jiang, Roger Glass, Duncan Steele, Jing Yu Tang, Zhong Shan Wang, Zhao Yin Fang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)

Abstract

During a rotavirus surveillance conducted in Lulong County, Hebei Province, China, a total of 331 stool specimens collected in 2003 from children under 5 years old with diarrhea were screened. We identified a novel group A human rotaviras of genotype G5P[6]. Phylogenetic analysis confirmed that the VP7 protein of this newly identified strain, LL36755, was closely related to those of the G5 strains. As such, it has 95.4% homology with its counterparts in the porcine GS strains C134 and CC117 at the amino acid sequence level. On the other hand, the VP4 protein of the LL36755 strain was 94.5% homologotis to those of the porcine P[6] strains 134/04-10, 134/04-11, 221/04-7, and 221/04-13. Our findings indicate a dynamic interaction between human and porcine rotaviruses.

Original languageEnglish
Pages (from-to)1614-1617
Number of pages4
JournalJournal of Clinical Microbiology
Volume45
Issue number5
DOIs
Publication statusPublished - May 2007
Externally publishedYes

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