Ongoing Strategies to Improve Antimicrobial Utilization in Hospitals across the Middle East and North Africa (MENA): Findings and Implications

Abdul Haseeb, Zikria Saleem*, Aseel Fayk Maqadmi, Roaa Abdulrahman Allehyani, Ahmad J. Mahrous, Mahmoud E. Elrggal, Sairah Hafeez Kamran, Manal AlGethamy, Asem Saleh Naji, Abdullmoin AlQarni, Khalid W. Alhariqi, Muhammad Arslan Khan, Kiran Ibrahim, Fahad Raees, Aisha Azmat, Aislinn Cook, Stephen M. Campbell, Giulia Lorenzetti, Johanna C. Meyer, Brian Godman*Catrin E. Moore

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Antimicrobial resistance (AMR) is an increasing global concern, increasing costs, morbidity, and mortality. National action plans (NAPs) to minimize AMR are one of several global and national initiatives to slow down rising AMR rates. NAPs are also helping key stakeholders understand current antimicrobial utilization patterns and resistance rates. The Middle East is no exception, with high AMR rates. Antibiotic point prevalence surveys (PPS) provide a better understanding of existing antimicrobial consumption trends in hospitals and assist with the subsequent implementation of antimicrobial stewardship programs (ASPs). These are important NAP activities. We examined current hospital consumption trends across the Middle East along with documented ASPs. A narrative assessment of 24 PPS studies in the region found that, on average, more than 50% of in-patients received antibiotics, with Jordan having the highest rate of 98.1%. Published studies ranged in size from a single to 18 hospitals. The most prescribed antibiotics were ceftriaxone, metronidazole, and penicillin. In addition, significant postoperative antibiotic prescribing lasting up to five days or longer was common to avoid surgical site infections. These findings have resulted in a variety of suggested short-, medium-, and long-term actions among key stakeholders, including governments and healthcare workers, to improve and sustain future antibiotic prescribing in order to decrease AMR throughout the Middle East.

Original languageEnglish
Article number827
Issue number5
Publication statusPublished - May 2023


  • Middle East
  • antimicrobial resistance
  • antimicrobial stewardship programs
  • antimicrobials
  • quality indicators
  • strategies
  • surgical site infections
  • utilization patterns


Dive into the research topics of 'Ongoing Strategies to Improve Antimicrobial Utilization in Hospitals across the Middle East and North Africa (MENA): Findings and Implications'. Together they form a unique fingerprint.

Cite this