TY - JOUR
T1 - Optimization of Green Synthesis of Nickel Nanoparticles by Halomonas Elongata as Antifungal Agent
AU - Safaei, Mohsen
AU - Imani, Mohammad Moslem
AU - Sharifi, Roohollah
AU - Salmani Mobarakeh, Mohammad
AU - Mozaffari, Hamid Reza
AU - Hashim, Mohd
AU - Wong, Ling Shing
AU - Nhlapo, Amos
AU - Rezaei, Razieh
N1 - Publisher Copyright:
© 2025 by SPC (Sami Publishing Company).
PY - 2024/11/1
Y1 - 2024/11/1
N2 - The current study aimed to investigate the optimum conditions for the green synthesis of nickel nanoparticles (NPs) with the highest antimicrobial activity instead of the Candida albicans. To this end, nine experiments were designed using the Taguchi method, and nickel NPs were synthesized biologically using the bacterium Halomonas elongata. According to the findings, the most suitable level for nickel nitrate, incubation temperature, and incubation duration was the third level (0.7 M), the second level (32 °C) and the first level (48 h), respectively. It was calculated that the NPs under synthesis in optimum conditions inhibited more than 72% of fungal growth. Moreover, the current study examined the features of nickel NPs under synthesis by various analyses that confirmed the formation of nickel NPs with favorable structural and morphological properties. Therefore, these nanoparticles can be used in medicine and dentistry as an effective antifungal compound.
AB - The current study aimed to investigate the optimum conditions for the green synthesis of nickel nanoparticles (NPs) with the highest antimicrobial activity instead of the Candida albicans. To this end, nine experiments were designed using the Taguchi method, and nickel NPs were synthesized biologically using the bacterium Halomonas elongata. According to the findings, the most suitable level for nickel nitrate, incubation temperature, and incubation duration was the third level (0.7 M), the second level (32 °C) and the first level (48 h), respectively. It was calculated that the NPs under synthesis in optimum conditions inhibited more than 72% of fungal growth. Moreover, the current study examined the features of nickel NPs under synthesis by various analyses that confirmed the formation of nickel NPs with favorable structural and morphological properties. Therefore, these nanoparticles can be used in medicine and dentistry as an effective antifungal compound.
KW - Antibacterial
KW - Green synthesis
KW - Human health
KW - Nickel nanoparticles
KW - Oral biofilm
UR - http://www.scopus.com/inward/record.url?scp=85210888929&partnerID=8YFLogxK
U2 - 10.48309/AJGC.2024.484242.1574
DO - 10.48309/AJGC.2024.484242.1574
M3 - Article
AN - SCOPUS:85210888929
SN - 2588-5839
VL - 8
SP - 779
EP - 793
JO - Asian Journal of Green Chemistry
JF - Asian Journal of Green Chemistry
IS - 6
ER -