Oral sarcoidosis: a case report and review of the literature

M. H. Motswaledi; R. A.G. Khammissa; Y. Jadwat; J. Lemmer; L. Feller

doi:10.1111/adj.12196

Oral sarcoidosis: a case report and review of the literature

M. H. Motswaledi, R. A.G. Khammissa, Y. Jadwat, J. Lemmer, L. Feller

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Sarcoidosis is a chronic multi-system immuno-inflammatory disorder characterized by non-caseating granulomatous infiltration of affected tissues that may result in fibrosis and organ dysfunction. It generally affects genetically predisposed young adults who develop a local dysregulated cell-mediated immune response towards an undefined 'sarcoidal antigen'. From recent data, it has become evident that Propionibacterium acnes and Mycobacterium tuberculosis are the probable antigenic agents which initiate sarcoidosis. Oral sarcoidosis is rare with only about 70 cases having been reported in the literature. The purpose of this report is to present a case of oral and cutaneous sarcoidosis in a black female that was probably triggered by mycobacteria.

Original language	English
Pages (from-to)	389-394
Number of pages	6
Journal	Australian Dental Journal
Volume	59
Issue number	3
DOIs	https://doi.org/10.1111/adj.12196
Publication status	Published - 1 Sept 2014
Externally published	Yes

Keywords

Mycobacterium
oral sarcoidosis
pathogenesis

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10.1111/adj.12196

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abstract = "Sarcoidosis is a chronic multi-system immuno-inflammatory disorder characterized by non-caseating granulomatous infiltration of affected tissues that may result in fibrosis and organ dysfunction. It generally affects genetically predisposed young adults who develop a local dysregulated cell-mediated immune response towards an undefined 'sarcoidal antigen'. From recent data, it has become evident that Propionibacterium acnes and Mycobacterium tuberculosis are the probable antigenic agents which initiate sarcoidosis. Oral sarcoidosis is rare with only about 70 cases having been reported in the literature. The purpose of this report is to present a case of oral and cutaneous sarcoidosis in a black female that was probably triggered by mycobacteria.",

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AB - Sarcoidosis is a chronic multi-system immuno-inflammatory disorder characterized by non-caseating granulomatous infiltration of affected tissues that may result in fibrosis and organ dysfunction. It generally affects genetically predisposed young adults who develop a local dysregulated cell-mediated immune response towards an undefined 'sarcoidal antigen'. From recent data, it has become evident that Propionibacterium acnes and Mycobacterium tuberculosis are the probable antigenic agents which initiate sarcoidosis. Oral sarcoidosis is rare with only about 70 cases having been reported in the literature. The purpose of this report is to present a case of oral and cutaneous sarcoidosis in a black female that was probably triggered by mycobacteria.

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Oral sarcoidosis: a case report and review of the literature

Abstract

Keywords

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