Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality

Jacqueline E. Tate; Manish M. Patel; Margaret M. Cortese; Benjamin A. Lopman; Jon R. Gentsch; Jessica Fleming; A. Duncan Steele; Umesh D. Parashar

doi:10.1586/erv.11.184

Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality

Jacqueline E. Tate^*, Manish M. Patel, Margaret M. Cortese, Benjamin A. Lopman, Jon R. Gentsch, Jessica Fleming, A. Duncan Steele, Umesh D. Parashar

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

31 Citations (Scopus)

Abstract

Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.

Original language	English
Pages (from-to)	211-220
Number of pages	10
Journal	Expert Review of Vaccines
Volume	11
Issue number	2
DOIs	https://doi.org/10.1586/erv.11.184
Publication status	Published - Feb 2012
Externally published	Yes

Keywords

diarrhea
rotavirus
rotavirus vaccine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1586/erv.11.184

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title = "Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality",

abstract = "Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.",

keywords = "diarrhea, rotavirus, rotavirus vaccine",

author = "Tate, {Jacqueline E.} and Patel, {Manish M.} and Cortese, {Margaret M.} and Lopman, {Benjamin A.} and Gentsch, {Jon R.} and Jessica Fleming and Steele, {A. Duncan} and Parashar, {Umesh D.}",

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AU - Tate, Jacqueline E.

AU - Patel, Manish M.

AU - Cortese, Margaret M.

AU - Lopman, Benjamin A.

AU - Gentsch, Jon R.

AU - Fleming, Jessica

AU - Steele, A. Duncan

AU - Parashar, Umesh D.

PY - 2012/2

Y1 - 2012/2

N2 - Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.

AB - Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.

KW - diarrhea

KW - rotavirus

KW - rotavirus vaccine

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DO - 10.1586/erv.11.184

M3 - Review article

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JO - Expert Review of Vaccines

JF - Expert Review of Vaccines

IS - 2

ER -

Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality

Abstract

Keywords

UN SDGs

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