Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality

Jacqueline E. Tate; Manish M. Patel; Margaret M. Cortese; Benjamin A. Lopman; Jon R. Gentsch; Jessica Fleming; A. Duncan Steele; Umesh D. Parashar

doi:10.1586/erv.11.184

Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality

Jacqueline E. Tate^*
, Manish M. Patel
, Margaret M. Cortese
, Benjamin A. Lopman
, Jon R. Gentsch
, Jessica Fleming
, A. Duncan Steele
, Umesh D. Parashar

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

33 Citations (Scopus)

Abstract

Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.

Original language	English
Pages (from-to)	211-220
Number of pages	10
Journal	Expert Review of Vaccines
Volume	11
Issue number	2
DOIs	https://doi.org/10.1586/erv.11.184
Publication status	Published - Feb 2012
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

diarrhea
rotavirus
rotavirus vaccine

Access to Document

10.1586/erv.11.184

Cite this

@article{edbbd5a3b2d649a2aafc1037ef532374,

title = "Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality",

abstract = "Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.",

keywords = "diarrhea, rotavirus, rotavirus vaccine",

author = "Tate, \{Jacqueline E.\} and Patel, \{Manish M.\} and Cortese, \{Margaret M.\} and Lopman, \{Benjamin A.\} and Gentsch, \{Jon R.\} and Jessica Fleming and Steele, \{A. Duncan\} and Parashar, \{Umesh D.\}",

year = "2012",

month = feb,

doi = "10.1586/erv.11.184",

language = "English",

volume = "11",

pages = "211--220",

journal = "Expert Review of Vaccines",

issn = "1476-0584",

publisher = "Taylor and Francis Ltd.",

number = "2",

}

TY - JOUR

T1 - Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality

AU - Tate, Jacqueline E.

AU - Patel, Manish M.

AU - Cortese, Margaret M.

AU - Lopman, Benjamin A.

AU - Gentsch, Jon R.

AU - Fleming, Jessica

AU - Steele, A. Duncan

AU - Parashar, Umesh D.

PY - 2012/2

Y1 - 2012/2

N2 - Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.

AB - Rotavirus vaccines have had a dramatic impact on morbidity and mortality from diarrhea among children in high- and middle-income countries that have introduced the vaccine into their national immunization programs. Widespread introduction of rotavirus vaccine in developing countries is imminent and their full potential in reducing the global burden from severe childhood diarrhea may soon be realized. The objectives of this paper are to describe the remaining issues and challenges in ensuring the success of the global rotavirus vaccination program and to discuss further research needed to help address them.

KW - diarrhea

KW - rotavirus

KW - rotavirus vaccine

UR - https://www.scopus.com/pages/publications/84856935991

U2 - 10.1586/erv.11.184

DO - 10.1586/erv.11.184

M3 - Review article

C2 - 22309669

AN - SCOPUS:84856935991

SN - 1476-0584

VL - 11

SP - 211

EP - 220

JO - Expert Review of Vaccines

JF - Expert Review of Vaccines

IS - 2

ER -

Remaining issues and challenges for rotavirus vaccine in preventing global childhood diarrheal morbidity and mortality

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this