Research priorities regarding rotavirus vaccine and intussusception: A meeting summary

Jacqueline E. Tate*, A. Duncan Steele, Julie E. Bines, Patrick L.F. Zuber, Umesh D. Parashar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Currently available rotavirus vaccines have been associated with a small increased risk of intussusception (∼1-2 cases per 100,000 vaccinated infants) in some populations. In response to this newly emerging data on intussusception related to current rotavirus vaccines, a group of technical experts convened by the Program for Applied Technology in Health met to review the data, establish what gaps in knowledge exist, and identify what future research is needed. This manuscript outlines the evidence that is currently available and the research agenda that was generated during this meeting. It also highlights the need for countries that are using or considering introducing the rotavirus vaccine to evaluate both the benefits and risks of vaccination.

Original languageEnglish
Pages (from-to)A179-A184
JournalVaccine
Volume30
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 27 Apr 2012
Externally publishedYes

Keywords

  • Intussusception
  • Rotavirus vaccine

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