Review of selective serotonin reuptake inhibitors

Audrey K. Chigome, Moreblessing M. Matsangaise, Byron O. Chukwu, Moliehi Matlala*, Mncengeli Sibanda, Johanna Catharina Meyer

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review

3 Citations (Scopus)


Selective serotonin reuptake inhibitors (SSRIs) are amongst the most widely prescribed class of antidepressants worldwide. Their extensive use is due to their better safety and effectiveness profile when compared to other classes of antidepressants. Several differences in pharmacology of the various SSRIs may affect the treatment choice in individual patients. This article summarises the role of SSRIs in the management of psychiatric and other disorders.
Original languageEnglish
Pages (from-to)52-59
Number of pages8
JournalSA Pharmaceutical Journal
Issue number6
Publication statusPublished - 1 Jan 2017


  • Antidepressants
  • Anxiety
  • Depression
  • Obsessive compulsive disorder
  • SSRI
  • Selective serotonin reuptake inhibitors


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