The molecular epidemiology of rotavirus infection in white children in Pretoria in Pretoria was investigated over a 2-year period. Rotavirus-positive specimens from 322 infants and young children submitted to private pathology laboratories were analysed by polyacrylamide-gel electrophoresis of the viral RNA. A predominance of long RNA profiles occurred and a temporal shift in the genomic patterns was identified. An epidemic of the classic shorter RNA profiles (suggestive of sub-group I rotaviruses) was observed in the winter of 1987, although these viruses were found less frequently than the sub-group II isolates (with a long RNA profile). Most neonatal isolates of rotaviruses exhibited a similar RNA electrophoretype, indicating that this strain of rotavirus was nosocomially acquired in different maternity units in the city.
|Number of pages||3|
|Journal||South African Medical Journal|
|Publication status||Published - 1991|