Statin prescribing among hypertensive patients in southwest Nigeria: Findings and implications for the future

Onyinye Onyeka Akunne; Brian Godman; Aduragbenro Deborah Adedapo; Ilse Truter; Joseph Fadare

doi:10.2217/cer.15.65

Statin prescribing among hypertensive patients in southwest Nigeria: Findings and implications for the future

Onyinye Onyeka Akunne, Brian Godman^*, Aduragbenro Deborah Adedapo, Ilse Truter, Joseph Fadare

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Background: Statins reduce cardiovascular risk, especially in patients with hypertension due to their concomitant blood pressure reducing effects. Prescribing generic statins minimizes cost and improves access. Aims: Ascertain current prescribing of statins in Nigeria and potential savings from the increased use of generic statins. Methods: Prospective study involving hypertensive patients attending University College Hospital (Ibadan, Nigeria). Results: In total, 228 hypertensive patients received statins. Atorvastatin was the most prescribed statin, followed by simvastatin, rosuvastatin and finally fluvastatin. Prescribed doses were less than one defined daily dose in the majority, with high use of originators. Average monthly potential savings from increased prescribing of generic statins was US$2635 for atorvastatin and US$10,578 for rosuvastatin. Conclusion: A shift toward increased prescribing generic statins is recommended to minimize costs.

Original language	English
Pages (from-to)	281-288
Number of pages	8
Journal	Journal of Comparative Effectiveness Research
Volume	5
Issue number	3
DOIs	https://doi.org/10.2217/cer.15.65
Publication status	Published - May 2016
Externally published	Yes

Keywords

Nigeria
costs
generics
hypertension
statins

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.2217/cer.15.65

Cite this

@article{5fb81ac773654a918192187ba4d33290,

title = "Statin prescribing among hypertensive patients in southwest Nigeria: Findings and implications for the future",

abstract = "Background: Statins reduce cardiovascular risk, especially in patients with hypertension due to their concomitant blood pressure reducing effects. Prescribing generic statins minimizes cost and improves access. Aims: Ascertain current prescribing of statins in Nigeria and potential savings from the increased use of generic statins. Methods: Prospective study involving hypertensive patients attending University College Hospital (Ibadan, Nigeria). Results: In total, 228 hypertensive patients received statins. Atorvastatin was the most prescribed statin, followed by simvastatin, rosuvastatin and finally fluvastatin. Prescribed doses were less than one defined daily dose in the majority, with high use of originators. Average monthly potential savings from increased prescribing of generic statins was US$2635 for atorvastatin and US$10,578 for rosuvastatin. Conclusion: A shift toward increased prescribing generic statins is recommended to minimize costs.",

keywords = "Nigeria, costs, generics, hypertension, statins",

author = "Akunne, {Onyinye Onyeka} and Brian Godman and Adedapo, {Aduragbenro Deborah} and Ilse Truter and Joseph Fadare",

note = "Publisher Copyright: {\textcopyright} 2016 Future Medicine Ltd.",

year = "2016",

month = may,

doi = "10.2217/cer.15.65",

language = "English",

volume = "5",

pages = "281--288",

journal = "Journal of Comparative Effectiveness Research",

issn = "2042-6305",

publisher = "Future Medicine Ltd.",

number = "3",

}

TY - JOUR

T1 - Statin prescribing among hypertensive patients in southwest Nigeria

T2 - Findings and implications for the future

AU - Akunne, Onyinye Onyeka

AU - Godman, Brian

AU - Adedapo, Aduragbenro Deborah

AU - Truter, Ilse

AU - Fadare, Joseph

PY - 2016/5

Y1 - 2016/5

N2 - Background: Statins reduce cardiovascular risk, especially in patients with hypertension due to their concomitant blood pressure reducing effects. Prescribing generic statins minimizes cost and improves access. Aims: Ascertain current prescribing of statins in Nigeria and potential savings from the increased use of generic statins. Methods: Prospective study involving hypertensive patients attending University College Hospital (Ibadan, Nigeria). Results: In total, 228 hypertensive patients received statins. Atorvastatin was the most prescribed statin, followed by simvastatin, rosuvastatin and finally fluvastatin. Prescribed doses were less than one defined daily dose in the majority, with high use of originators. Average monthly potential savings from increased prescribing of generic statins was US$2635 for atorvastatin and US$10,578 for rosuvastatin. Conclusion: A shift toward increased prescribing generic statins is recommended to minimize costs.

AB - Background: Statins reduce cardiovascular risk, especially in patients with hypertension due to their concomitant blood pressure reducing effects. Prescribing generic statins minimizes cost and improves access. Aims: Ascertain current prescribing of statins in Nigeria and potential savings from the increased use of generic statins. Methods: Prospective study involving hypertensive patients attending University College Hospital (Ibadan, Nigeria). Results: In total, 228 hypertensive patients received statins. Atorvastatin was the most prescribed statin, followed by simvastatin, rosuvastatin and finally fluvastatin. Prescribed doses were less than one defined daily dose in the majority, with high use of originators. Average monthly potential savings from increased prescribing of generic statins was US$2635 for atorvastatin and US$10,578 for rosuvastatin. Conclusion: A shift toward increased prescribing generic statins is recommended to minimize costs.

KW - Nigeria

KW - costs

KW - generics

KW - hypertension

KW - statins

UR - http://www.scopus.com/inward/record.url?scp=84969820482&partnerID=8YFLogxK

U2 - 10.2217/cer.15.65

DO - 10.2217/cer.15.65

M3 - Article

C2 - 27097045

AN - SCOPUS:84969820482

SN - 2042-6305

VL - 5

SP - 281

EP - 288

JO - Journal of Comparative Effectiveness Research

JF - Journal of Comparative Effectiveness Research

IS - 3

ER -

Statin prescribing among hypertensive patients in southwest Nigeria: Findings and implications for the future

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this