Sublingual immunotherapy for the treatment of allergies

Natalie Schellack*, Deirdre Engler

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review


© 2016 The Author(s). The treatment of allergies often involves pharmacological therapy and recommendations by healthcare workers that the allergen should be avoided. Allergen-specific immunotherapy has emerged as an alternative to effectively decrease the immunoglobulin (Ig) E:IgG4 ratio. Two routes of administration are described, namely subcutaneous immunotherapy, which has always been considered to be the gold standard of treatment, and sublingual immunotherapy, which has recently been shown to have fewer systemic side-effects and improved compliance by patients.
Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalSouth African Family Practice
Issue number2
Publication statusPublished - 1 Jan 2016


  • AIT
  • Allergen-specific immunotherapy
  • Allergic disease
  • Allergic rhinitis
  • Clinical efficacy
  • SCIT
  • SLIT
  • Subcutaneous immunotherapy
  • Sublingual immunotherapy


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