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Top-down synthesis of a lamivudine-zidovudine nano Co-Crystal
Bwalya A. Witika
, Vincent J. Smith
, Roderick B. Walker
*
*
Corresponding author for this work
Research output
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Contribution to journal
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Article
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peer-review
27
Citations (Scopus)
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Keyphrases
Lamivudine
100%
Zidovudine
100%
Nano-co-crystal
100%
Top-down Synthesis
100%
Response Surface Methodology
33%
Sodium Lauryl Sulfate
33%
Critical Quality Attributes
33%
Polydispersity Index
33%
Zeta Potential
33%
Design of Experiments
33%
D-α-tocopheryl Polyethylene Glycol 1000 Succinate
33%
AIDS/HIV
16%
Transmission Electron Microscopy
16%
Particle Size
16%
Energy Dispersive X-ray Spectroscopy
16%
Fourier Transform Infrared Spectroscopy (FT-IR)
16%
Differential Scanning Calorimetry
16%
Nanocrystals
16%
Powder X-ray Diffraction
16%
Antiretroviral Agents
16%
Surfactant
16%
Cocrystal
16%
Cytotoxicity Assay
16%
Size-polydispersity
16%
Mean Particle Size
16%
Rapid Methods
16%
Precise Method
16%
Media Milling
16%
Solvent Evaporation
16%
Milling Time
16%
Milling Media
16%
Scanning Electron Microscopy (SEM-EDS)
16%
Number of Units
16%
Inexpensive Method
16%
Pharmacology, Toxicology and Pharmaceutical Science
Lamivudine
100%
Zidovudine
100%
Lamivudine Plus Zidovudine
100%
Macrogol
66%
Zeta Potential
66%
Succinic Acid
66%
Sodium Dodecyl Sulfate
66%
Infection
33%
HIV
33%
Differential Scanning Calorimetry
33%
Scanning Electron Microscopy
33%
Fourier Transform Infrared Spectroscopy
33%
Acquired Immune Deficiency Syndrome
33%
Cytotoxicity Assay
33%
Transmission Electron Microscopy
33%
Antiretrovirus Agent
33%
Surfactant
33%
Nanocrystal
33%