O-Mesyloximes derived from 2-aryl-1,2,3,4-tetrahydro-1-methylsulfonyl-4-quinolones react with sodium ethoxide in ethanol to afford the 4-amino-2-arylquinolines in high yield. No traces of the 3-amino-2-aryl-4-quinolones expected from the Neber rearrangement of the substrates were detected or isolated from the reaction mixture. The structures of the products were determined using a combination of 1H NMR, 13C NMR, IR and mass spectroscopic techniques.
|Number of pages||12|
|Journal||Phosphorus, Sulfur and Silicon and the Related Elements|
|Publication status||Published - 2000|
- Neber rearrangement
- O-mesyloxime 2-aryl-1; 2; 3; 4-tetrahydro-1-methylsulfonyl-4-quinolone derivatives